Type 2 Disease Models Risk Factors Sleep Apnea Adipocyte Obstructive Skin Acetylcholine Lipid Metabolism Aorta Cancer Physiologic Angiogenesis Oxidative Stress Apoptosis Adult Ischemia Metabolic syndrome Wistar Blotting Animals Sonic hedgehog Aged Endothelial dysfunction Female Atherosclerosis Diabetes Nitric oxide Caveolin 1 Polyphenols 3T3-L1 Cells Cells Endothelium Humans Liver Retrospective Studies Lipids Caveolins Microvesicles Male Cardiovascular Diseases Cystic fibrosis Vascular Inflammation Cell Line Mice Signal Fibroblasts Vasodilation Exosomes Mutation Adipocytes Metabolomics Dose-Response Relationship Knockout Mitochondria Body Mass Index Cell-Derived Blood Thyroid Pulmonary Extracellular vesicles Neovascularization Middle Aged Obesity Nitric Messenger Rats Cardiovascular Dysfonction endothéliale Lipodystrophy Young Adult Clusiaceae Cultured Microparticules Adrenergic Membrane Signal Transduction Endothelial Cells Cell-Derived Microparticles Flavonoids RNA Biological Adolescent Phenotype Aging Receptors Endothelial Mitochondrial Cell Body Weight Drug Oxidative Hypertension Microparticles Adipose tissue Caveolae Oxidative stress Animal Cardiology