Mosaic deficiency in mitochondrial oxidative metabolism promotes cardiac arrhythmia during aging, Cell Metab, vol.21, pp.667-77, 2015. ,
The mitochondrial electron transport chain is dispensable for proliferation and differentiation of epidermal progenitor cells, Stem Cells, vol.29, 2011. ,
Singlet oxygen mediates the UVA-induced generation of the photoagingassociated mitochondrial common deletion, J Biol Chem, vol.274, pp.15345-15354, 1999. ,
Mitochondrial DNA deletions in human skin reflect photo-rather than chronologic aging, J Invest Dermatol, vol.110, pp.149-52, 1998. ,
Multiple functions of the new cytokinebased antimicrobial peptide thymic stromal lymphopoietin (TSLP), Pharmaceuticals, vol.9, issue.3, p.41, 2016. ,
Mitochondrial fusion is required for mtDNA stability in skeletal muscle and tolerance of mtDNA mutations, Cell, vol.141, pp.280-289, 2010. ,
Rapamycin drives selection against a pathogenic heteroplasmic mitochondrial DNA mutation, Hum Mol Genet, vol.23, pp.637-684, 2014. ,
Mitochondrial DNA deletions serve as biomarkers of aging in the skin, but are typically absent in nonmelanoma skin cancers, J Invest Dermatol, vol.126, pp.336-380, 2006. ,
Inflammaging and 'Garb-aging, Trends Endocrin Met, vol.28, 2017. ,
Mitochondria: master regulators of danger signalling, Nat Rev Mol Cell Biol, vol.13, pp.780-788, 2012. ,
Twinkle mutations associated with autosomal dominant progressive external ophthalmoplegia lead to impaired helicase function and in vivo mtDNA replication stalling, Hum Mol Genet, vol.18, pp.328-368, 2009. ,
Mitochondria: diversity in the regulation of the NLRP3 inflammasome, Trends Mol Med, vol.21, pp.193-201, 2015. ,
Keratin 14 Cre transgenic mice authenticate keratin 14 as an oocyteexpressed protein, Genesis, vol.38, pp.176-81, 2004. ,
Mitochondrial reactive oxygen species promote epidermal differentiation and hair follicle development, Sci Signal, vol.6, issue.261, p.8, 2013. ,
Mitochondrial reactive oxygen species induces NLRP3-dependent lysosomal damage and inflammasome activation, J Immunol, vol.191, pp.5230-5238, 2013. ,
Nonsense mutations in the COX1 subunit impair the stability of respiratory chain complexes rather than their assembly, EMBO J, vol.31, pp.1293-307, 2012. ,
Sensory ataxic neuropathy due to a novel C10Orf2 mutation with probable germline mosaicism, Neurology, vol.64, pp.371-374, 2005. ,
IL-33 induces skin inflammation with mast cell and neutrophil activation, Eur J Immunol, vol.41, pp.2229-2266, 2011. ,
Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero, Dev Cell, vol.23, pp.1238-1284, 2012. ,
Mitochondrial cardiolipin is required for Nlrp3 inflammasome activation, Immunity, vol.39, pp.311-334, 2013. ,
Chronic inflammation induces telomere dysfunction and accelerates ageing in mice, Nat Comm, vol.2, p.4172, 2014. ,
Mitochondrial function in murine skin epithelium is crucial for hair follicle morphogenesis and epithelial-mesenchymal interactions, J Invest Dermatol, vol.135, pp.679-89, 2015. ,
Lessons from loricrin-deficient mice: compensatory mechanisms maintaining skin barrier function in the absence of a major cornified envelope protein, J Cell Biol, vol.151, pp.389-400, 2000. ,
The use of a 3895 bp mitochondrial DNA deletion as a marker for sunlight exposure in human skin, J Invest Dermatol, vol.123, pp.1020-1024, 2004. ,
Tumor necrosis factor receptor signaling in keratinocytes triggers interleukin-24-dependent psoriasis-like skin inflammation in mice, Immunity, vol.39, pp.899-911, 2013. ,
Somatic mitochondrial DNA mutations in mammalian aging, Annu Rev Biochem, vol.79, pp.683-706, 2010. ,
Immune signaling by RIG-I-like receptors, Immunity, vol.34, pp.680-92, 2011. ,
Catecholamine metabolism induces mitochondrial DNA deletions and leads to severe adrenal degeneration during aging, Neuroendocrinology, vol.104, pp.72-84, 2017. ,
S100A8/A9, a key mediator for positive feedback growth stimulation of normal human keratinocytes, J Cell Biochem, vol.104, pp.453-64, 2008. ,
Aging and immune function: molecular mechanisms to interventions, Antioxd Redox Signal, vol.14, pp.1551-85, 2011. ,
The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin, J Invest Dermatol, vol.115, pp.674-683, 2000. ,
Mitochondrial and inflammatory changes in sporadic inclusion body myositis, Neuropathol Appl Neurobiol, vol.41, pp.288-303, 2015. ,
Cytochemistry and immunocytochemistry of mitochondria in tissue sections, Methods Enzymol, vol.264, pp.509-530, 1996. ,
Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis, Immunity, vol.36, pp.401-415, 2012. ,
Human mitochondrial DNA deletions associated with mutations in the gene encoding Twinkle, a phage T7 gene 4-like protein localized in mitochondria, Nat Genet, vol.28, pp.223-254, 2001. ,
Cell degeneration in alopecia areata. An ultrastructural study, Am J Dermatopathol, vol.13, pp.248-56, 1991. ,
Mitochondria in autoinflammation: cause, mediator or bystander?, Trends Endocrinol Metab, vol.26, pp.263-71, 2015. ,
Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy, Acta Neuropathol, vol.132, pp.277-88, 2016. ,
Circulating mitochondrial DAMPs cause inflammatory responses to injury, Nature, vol.464, issue.7285, pp.104-111, 2010. ,
Inflammaging in skin and other tissues-the roles of complement system and macrophage, Inflamm Allergy Drug Targets, vol.13, pp.153-61, 2014. ,
Clinical aspects and molecular diagnostics of skin aging, Clin Dermatol, vol.29, pp.3-14, 2011. ,