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Communication dans un congrès

Development of an eco-friendly Thermal Induced Phase Separation (TIPS) process assisted by supercritical CO2 for the production of PLA scaffolds with tunable structural and mechanical properties

Abstract :

Many routes are nowadays utilized for the production of PLA scaffolds. In this study, a relative large scale of scaffolds was produced combining thermal induced phase separation and supercritical CO2 as a green alternative drying. The phase separation between polylactic acid and 1,4-dioxane was monitored by adjusting the process parameters such as the polymer concentration, the molecular weight, the solvent power and the cooling conditions. The morphologic changes occurring during the phase separation were analyzed by scanning electron microscopy. Structural and mechanical properties of scaffolds were correlated and it was possible to tune them depending on the process parameters. Moreover, an environmental analysis of the thermal induced phase separation (TIPS) process and the comparison between supercritical CO2 and the traditional freeze drying technologies were investigated. This work is the first known attempt to conduct the life cycle assessment (LCA) methodology on TIPS process and the polylactic acid scaffolds production. The results of the LCA have demonstrated that using supercritical-CO2 drying technology allows to reduce by at least 50 % the environmental impact of the whole process and to drastically diminish the production time.

Type de document :
Communication dans un congrès
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https://hal.univ-angers.fr/hal-02616011
Contributeur : Okina Université d'Angers <>
Soumis le : dimanche 24 mai 2020 - 03:39:34
Dernière modification le : vendredi 19 juin 2020 - 03:09:17

Identifiants

  • HAL Id : hal-02616011, version 1
  • OKINA : ua17020

Citation

Guillaume Lefebvre, Swann Gay, Marie Bonnin, Benjamin Nottelet, Frank Boury, et al.. Development of an eco-friendly Thermal Induced Phase Separation (TIPS) process assisted by supercritical CO2 for the production of PLA scaffolds with tunable structural and mechanical properties. 16th European Meeting on Supercritical Fluids, 2017, Lisbonne, Portugal. ⟨hal-02616011⟩

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