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Article dans une revue

A Novel FibroScan Examination Dedicated to Spleen Stiffness Measurement.

Abstract :

Esophageal varices (EVs) are among the most severe complications of cirrhosis, with a prevalence of 50% to 60% among cirrhotic patients. International guidelines therefore recommend that cirrhotic patients should be screened for the presence of EVs. The main objective of this study was to introduce a new spleen-dedicated FibroScan (Echosens, Paris, France) examination and to assess its performance in detecting large EVs (grade 2 and 3). This novel examination has been validated in simulation and phantom studies and has been used in a population of patients with chronic liver disease. The study described here suggests that the novel spleen-dedicated FibroScan examination performs better than the standard FibroScan for the detection of large EVs (area under the curve = 0.70 for the standard examination and 0.79 [p <0.01] for the spleen examination), but further clinical studies are needed to investigate the role of spleen stiffness in the management of cirrhotic patients.

Type de document :
Article dans une revue
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Contributeur : Okina Université d'Angers <>
Soumis le : vendredi 29 mai 2020 - 09:34:00
Dernière modification le : lundi 26 avril 2021 - 16:40:03




Cécile Bastard, Véronique Miette, P. Calès, Horia Stefanescu, Davide Festi, et al.. A Novel FibroScan Examination Dedicated to Spleen Stiffness Measurement.. Ultrasound Med Biol, 2018, 44 (8), pp.1616-1626. ⟨10.1016/j.ultrasmedbio.2018.03.028⟩. ⟨hal-02648430⟩



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