Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

The Weaning Index combining EtCO2 and respiratory rate early identifies Spontaneous Breathing trial failure. A pilot study

Abstract :

BACKGROUND: We aimed to evaluate the predictive value of the end-tidal CO2 (EtCO2) alone or combined with ventilation related parameters on spontaneous breathing trial (SBT) outcome on mechanically ventilated patients.

METHODS: Prospective observational study in a medical ICU. Mechanically ventilated adult patients who met predefined criteria for weaning were included. Patients underwent a T-piece SBT for 30 minutes and the usual hemodynamic and respiratory clinical parameters including EtCO2 were recorded every 5 minutes.

RESULTS: 280 patients were studied (age: 64±17 years, SAPS II: 44 [34-56]) during a first SBT and 76 patients during a second SBT. The Weaning Index, defined as the product of the respiratory rate and EtCO2, was a strong early predictive factor of SBT outcome; at 10 minutes, the area under the curve (AUC) was 86% ([80-90], P<0.0001) during the first SBT and 88% ([80-96], P<0.0001) during the second SBT. After 10 minutes of SBT, a Weaning Index >1100 identified patients that will not successfully complete the SBT at 30 minutes with a specificity of 98%.

CONCLUSIONS: In unselected mechanically ventilated patients, the Weaning Index is helpful to early identify patients who will fail the SBT during a first and a second trial.

Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal.univ-angers.fr/hal-02874619
Contributeur : Okina Université d'Angers <>
Soumis le : vendredi 19 juin 2020 - 04:05:29
Dernière modification le : mardi 1 septembre 2020 - 03:21:47

Identifiants

Citation

Jean-Luc Baudel, Vincent Dubée, Pierre-Yves Boëlle, Simon Bourcier, Guillaume Leblanc, et al.. The Weaning Index combining EtCO2 and respiratory rate early identifies Spontaneous Breathing trial failure. A pilot study. Minerva Anestesiologica, Edizione Minerva Medica, 2019, 85 (4), pp.384-392. ⟨10.23736/S0375-9393.18.13108-7⟩. ⟨hal-02874619⟩

Partager

Métriques

Consultations de la notice

44