Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Synthesis, characterisation and antifungal activity of a series of Cobalt(II) and Nickel(II) complexes with ligands derived from reduced N, N′-o-Phenylenebis(Salicylideneimine)

Abstract : The synthesis and characterisation by elemental analysis, conductivity, FTIR, UV-Visible, ESR and magnetic measurements are described for a series of complexes of nickel(II) and cobalt(II) with three ligands (H 2 L 1-3) derived from reduced N, N 0-o-Phenylenebis(salicylideneimine). The complexes formed are identified as neutral species, where the ligands are coordinated through N and O donor atoms. The formulae obtained for the complexes are: [CoL(H 2 O) 2 ] with octahedral geometry and [NiL] with tetrahedral geometry. Their antifungal activity is evaluated towards human pathogenic fungi including yeasts of the Candida genus, some opportunistic moulds belonging to the Aspergillus, Scedosporium genus and some dermatophytes. The cobalt complexes show a significant growth inhibition of yeasts tested and also to fungi of the genus Scedosporium which is of interest because these fungi are usually poorly susceptible to current antifungal including Amphotericin B and Itraconazole, chosen as reference in this study. The activity data show that the metal complexes are more potent than the parent ligand.
Type de document :
Article dans une revue
Domaine :
Liste complète des métadonnées

https://hal.univ-angers.fr/hal-03243913
Contributeur : Mustayeen Khan <>
Soumis le : jeudi 3 juin 2021 - 19:14:59
Dernière modification le : vendredi 4 juin 2021 - 10:06:02
Archivage à long terme le : : samedi 4 septembre 2021 - 18:02:28

Fichier

2008-Transition Met Chem-Sabri...
Accord explicite pour ce dépôt

Identifiants

Collections

Citation

Sabrina Belaïd, Anne Landreau, Safia Djebbar, Ouassini Benali-Baïtich, Mustayeen Khan, et al.. Synthesis, characterisation and antifungal activity of a series of Cobalt(II) and Nickel(II) complexes with ligands derived from reduced N, N′-o-Phenylenebis(Salicylideneimine). Transition Metal Chemistry, Springer Verlag, 2008, 33 (4), pp.511-516. ⟨10.1007/s11243-008-9073-z⟩. ⟨hal-03243913⟩

Partager

Métriques

Consultations de la notice

11

Téléchargements de fichiers

17