Post-treatment MRI aspects of photodynamic therapy for prostate cancer
Résumé
OBJECTIVES: Photodynamic therapy is a new focal therapy for prostate cancer.
METHODS: In this technique, a photosensitising agent is introduced intravenously, then activated by local laser illumination to induce tumour necrosis. Treatment efficacy is assessed by magnetic resonance imaging (MRI).
RESULTS AND CONCLUSIONS: We illustrate specific post-treatment MRI aspects at early and late follow-up with pathological correlations.
TEACHING POINTS:
Dynamic phototherapy is a new and promising focal therapy for prostate cancer.
One-week MRI shows increased volume of the treated lobe and large, homogeneous necrosis area.
Six-month MRI shows significant changes of the prostate shape and signal.
Six-month MRI becomes "base line" appearance for further follow-up or monitoring.