Accéder directement au contenu Accéder directement à la navigation
Article dans une revue

Renal function after partial nephrectomy following intra-arterial embolization of renal tumors

Abstract : Abstract Laparoscopic Partial Nephrectomy (LPN) after intra-arterial Embolization of renal tumors (LPNE) in a hybrid operating room allows renal tumor enucleation without dissection and clamping of the renal pedicle. The purpose was to assess the potential negative impact of embolization on the renal function. This prospective monocentric study included all patients treated with LPNE between May 2015 and June 2019. Clinical data was collected and incorporated into the UroCCR database (NCT03293563). Glomerular Filtration Rate (GFR) and Computed Tomography Renal Volume (CTRV) were compared before and after 6 months following LPNE. The mean post-operative GFR was 86.6 mL/min (SD 22.9). The mean GFR loss was 9.4% (SD 15.1) and the median renal parenchyma loss was 21 mL (SD 20.6). Using a threshold of 25% GFR loss, age was the only significant predictive factor of renal function impairment according to bivariate (59.5 vs 69.3 years, p = 0.017) and multivariable analysis (OR 1.075, CI 1–1.2], p = 0.05). Significant renal function impairment was not correlated with the renal parenchymal volume loss (OR 0.987, CI [0.95–1.02], p = 0.435). Renal function impairment after LPNE seems to be comparable to other techniques of partial nephrectomy.
Type de document :
Article dans une revue
Liste complète des métadonnées

https://hal.univ-angers.fr/hal-03292786
Contributeur : Véronique Bourgeais <>
Soumis le : mardi 20 juillet 2021 - 15:47:46
Dernière modification le : mercredi 28 juillet 2021 - 10:30:43

Lien texte intégral

Identifiants

Collections

Citation

Germain Bréhier, Antoine Bouvier, Louis Besnier, Serge Willoteaux, Cosmina Nedelcu, et al.. Renal function after partial nephrectomy following intra-arterial embolization of renal tumors. Scientific Reports, Nature Publishing Group, 2020, 10 (1), ⟨10.1038/s41598-020-78461-5⟩. ⟨hal-03292786⟩

Partager

Métriques

Consultations de la notice

4