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Article dans une revue

Injectable biphasic calcium phosphate bioceramic: The HYDROS® concept

Abstract :

A new biphasic calcium phosphate ceramic material has been developed in our laboratory. It is composed of 60% of hydroxyapatite and 40% of β-tricalcium phosphate, based on three granulometries (submicron, round microporous 80-200 mum and macro microporous 0.5-1 mm particles) and hydrated with water leading the formation of a putty filler for bone repair. Biocompatibility and osteogenicity were tested by filling femoral epiphyses critical size bone defect and lumbar muscles in rabbit. After 3, 6 and 12 weeks of implantation, explants were treated for histology. Results revealed the biocompatibility of the material and intensive resorption of the submicron particle fraction followed by important bone ingrowth whereas osteoconduction was provided by the larger particles.

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Soumis le : mardi 21 septembre 2021 - 10:07:22
Dernière modification le : mercredi 19 janvier 2022 - 16:26:02




Serge Baroth, Xavier Bourges, Eric Goyenvalle, Eric Aguado, Guy Daculsi. Injectable biphasic calcium phosphate bioceramic: The HYDROS® concept. Bio-Medical Materials and Engineering, 2009, 19 (1), pp.71-76. ⟨10.3233/BME-2009-0565⟩. ⟨hal-03350071⟩



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