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Communication dans un congrès

Multi-Neighborhood Search for Discrimination of Signal Peptides and Transmembrane Segments

Abstract :

A key step in study of biosynthesis of membrane proteins is to look for the code that could be used to explain and predict which proteins would eventually be inserted in the membrane and which proteins would be secreted into the ER lumen when they cross the translocon channel. The aim of this work is to present an improvement of a previous method based on a local search approach. The proposed method relies on new in-depth biological observations to design a new search space for the local search algorithm. Experiments conducted on a dedicated dataset show that our new approach leads to improved outcomes in terms of prediction rates.

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Communication dans un congrès
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https://hal.univ-angers.fr/hal-03350610
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Soumis le : mardi 21 septembre 2021 - 14:34:37
Dernière modification le : mercredi 20 octobre 2021 - 03:19:09

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Sami Laroum, Béatrice Duval, Dominique Tessier, Jin-Kao Hao. Multi-Neighborhood Search for Discrimination of Signal Peptides and Transmembrane Segments. 9th European Conference, EvoBIO 2011, 2011, Turin, Italy. pp.111 - 122, ⟨10.1007/978-3-642-20389-3_11⟩. ⟨hal-03350610⟩

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