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Communication dans un congrès

Global Perturbation of Initial Geometry in a Biomechanical Model of Cortical Morphogenesis

Abstract : Cortical folding pattern is a main characteristic of the geometry of the human brain which is formed by gyri (ridges) and sulci (grooves). Several biological hypotheses have suggested different mechanisms that attempt to explain the development of cortical folding and its abnormal evolutions. Based on these hypotheses, biomechanical models of cortical folding have been proposed. In this work, we compare biomechanical simulations for several initial conditions by using an adaptive spherical parameterization approach. Our approach allows us to study and explore one of the most potential sources of reproducible cortical folding pattern: the specification of initial geometry of the brain.
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https://hal.univ-angers.fr/hal-02510179
Contributeur : Marie-Françoise Gerard <>
Soumis le : mardi 17 mars 2020 - 15:09:13
Dernière modification le : mercredi 18 mars 2020 - 01:35:17

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A. Bohi, X. Wang, M. Harrach, Mickaël Dinomais, F. Rousseau, et al.. Global Perturbation of Initial Geometry in a Biomechanical Model of Cortical Morphogenesis. 2019 41st Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC), Jul 2019, Berlin, France. pp.442-445, ⟨10.1109/EMBC.2019.8856723⟩. ⟨hal-02510179⟩

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